Publications

Explainable artificial intelligence for mental health through transparency and interpretability for understandability
The literature on artificial intelligence (AI) or machine learning (ML) in mental health and psychiatry lacks consensus on what …
PDF Cite DOI
A participatory initiative to include LGBT+ voices in AI for mental health
Artificial intelligence (AI) can help clinicians to improve healthcare decision-making by integrating data from high-volume, …
PDF Cite DOI
CHRONOSIG: Digital Triage for Secondary Mental Healthcare using Natural Language Processing - rationale and protocol
Accessing specialist secondary mental health care in the NHS in England requires a referral, usually from primary or acute care. …
PDF Cite DOI
Refining the Analysis of Multidimensional Psychometric Data: A Geometric Distance Approach
Validated instruments such as questionnaires, patient-reported outcome measures and clinician-rated psychopathology scales, are …
PDF Cite DOI
Changes in daily mental health service use and mortality at the commencement and lifting of COVID-19 ‘lockdown’ policy in 10 UK sites: a regression discontinuity in time design
To investigate changes in daily mental health (MH) service use and mortality in response to the introduction and the lifting of the …
Cite DOI
Cognitive performance in early, treatment-resistant psychosis patients: Could cognitive control play a role in persistent symptoms?
Approximately one third of psychosis patients fail to respond to conventional antipsychotic medication, which exerts its effect via …
Cite DOI
The temporal dynamics of sleep disturbance and psychopathology in psychosis: a digital sampling study
Sleep disruption is a common precursor to deterioration and relapse in people living with psychotic disorders. Understanding the …
Cite DOI
Examination of the neural basis of psychotic-like experiences in adolescence during processing of emotional faces
Contemporary theories propose that dysregulation of emotional perception is involved in the aetiology of psychosis. 298 healthy …
Cite DOI
When Deploying Predictive Algorithms, Are Summary Performance Measures Sufficient?
The last decade’s growth in artificial intelligence, machine learning, and statistical methods for high-dimensional data has driven a …
PDF Cite DOI
A symptom combination predicting treatment-resistant schizophrenia – A strategy for real-world clinical practice
Early identification of symptoms that can predict treatment-resistant schizophrenia (TRS) could help clinicians to avoid delays in …
PDF Cite DOI
Exacerbation of Psychosis During the Perimenstrual Phase of the Menstrual Cycle: Systematic Review and Meta-analysis
Psychotic disorders can be exacerbated by the hormonal changes associated with childbirth, but the extent to which exacerbations occur …
PDF Cite DOI
Associations Between Non-neurological Autoimmune Disorders and Psychosis: A Meta-analysis.
BACKGROUND: A relationship between non-neurological autoimmune (NNAI) disorders and psychosis has been widely reported but not yet …
Cite DOI
Integration is not necessarily at odds with reductionism.
Cite DOI
Examination of the Neural Basis of Psychoticlike Experiences in Adolescence During Reward Processing.
Importance: Psychoticlike experiences (PLEs) are subclinical manifestations of psychotic symptoms and may reflect an increased …
Cite DOI
Improving the quality of physical health monitoring in CAMHS for children and adolescents prescribed medication for ADHD.
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterised by a persistent, pervasive …
Cite DOI
Are we failing clinical trials? A case for strong aggregate outcomes.
Clinical trials in psychiatry inherit methods for design and statistical analysis from evidence-based medicine. However, trials in …
Cite DOI
Parsing the Roles of the Frontal Lobes and Basal Ganglia in Task Control Using Multivoxel Pattern Analysis.
Cognitive control has traditionally been associated with pFC based on observations of deficits in patients with frontal lesions. …
Cite DOI
Realising stratified psychiatry using multidimensional signatures and trajectories.
BACKGROUND: Stratified or personalised medicine targets treatments for groups of individuals with a disorder based on individual …
Cite DOI
Reduced susceptibility to the sound-induced flash fusion illusion in schizophrenia.
Schizophrenia is characterised by the presence of abnormal complex sensory perceptual experiences. Such experiences could arise as a …
Cite DOI
Cognitive and oculomotor performance in subjects with low and high schizotypy: implications for translational drug development studies.
The development of drugs to improve cognition in patients with schizophrenia is a major unmet clinical need. A number of promising …
Cite DOI
Dysfunctional Striatal Systems in Treatment-Resistant Schizophrenia.
The prevalence of treatment-resistant schizophrenia points to a discrete illness subtype, but to date its pathophysiologic …
Cite DOI
Skating on thin ice: pragmatic prescribing for medication refractory schizophrenia.
BACKGROUND: Clozapine is the treatment of choice for medication refractory psychosis, but it does not benefit half of those put on it. …
Cite DOI
Amphetamine sensitisation and memory in healthy human volunteers: a functional magnetic resonance imaging study.
Amphetamine sensitisation (AS) is an established animal model of the hypersensitivity to psychostimulants seen in patients with …
Cite DOI
Functional magnetic resonance imaging of impaired sensory prediction in schizophrenia.
IMPORTANCE: Forward models predict the sensory consequences of planned actions and permit discrimination of self- and non-self-elicited …
Cite DOI
Eluding the illusion? Schizophrenia, dopamine and the McGurk effect.
Perceptions are inherently probabilistic; and can be potentially manipulated to induce illusory experience by the presentation of …
Cite DOI
Amphetamine sensitization alters reward processing in the human striatum and amygdala.
Dysregulation of mesolimbic dopamine transmission is implicated in a number of psychiatric illnesses characterised by disruption of …
Cite DOI
Examining belief and confidence in schizophrenia.
BACKGROUND: People with psychoses often report fixed, delusional beliefs that are sustained even in the presence of unequivocal …
Cite DOI
Trust versus paranoia: abnormal response to social reward in psychotic illness.
Psychosis is characterized by an elementary lack of trust in others. Trust is an inherently rewarding aspect of successful social …
Cite DOI
Aging effects on functional auditory and visual processing using fMRI with variable sensory loading.
INTRODUCTION: Traditionally, studies investigating the functional implications of age-related structural brain alterations have focused …
Cite DOI
Modulation of somatosensory processing by action.
Psychophysical evidence suggests that sensations arising from our own movements are diminished when predicted by motor forward models …
Cite DOI
Sexual quality of life in women who have undergone female genital mutilation: a case-control study.
OBJECTIVE: To investigate the sexual quality of life of women who have undergone female genital mutilation (FGM) and compare them with …
Cite DOI
To trust or not to trust: the dynamics of social interaction in psychosis.
Psychotic illness is a disorder of social interaction unique to humans. However, up to now research has failed to pin down the exact …
Cite DOI
Functional magnetic resonance imaging investigation of the amphetamine sensitization model of schizophrenia in healthy male volunteers.
CONTEXT: Recent work suggests that the amphetamine sensitization model of schizophrenia can safely be induced in healthy volunteers and …
Cite DOI
Spatial language, visual attention, and perceptual simulation.
Spatial language descriptions, such as The bottle is over the glass, direct the attention of the hearer to particular aspects of the …
Cite DOI
An evoked auditory response fMRI study of the effects of rTMS on putative AVH pathways in healthy volunteers.
BACKGROUND: Auditory verbal hallucinations (AVH) are the most prevalent symptom in schizophrenia. They are associated with increased …
Cite DOI
Kinematic cues in perceptual weight judgement and their origins in box lifting.
When accepting a parcel from another person, we are able to use information about that person’s movement to estimate in advance …
Cite DOI
Passive processing of visual and auditory stimuli in the young and elderly: a neuroimaging study
Cite
Spatial prepositions and vague quantifiers: Implementing the functional geometric framework
Cite
On the foundations of perceptual symbol systems: Specifying embodied representations via connectionism
Cite
Putting geometry and function together-towards a psychologically-plausible computational model for spatial language comprehension
Cite
Object representation-by-fragments in the visual system: A neurocomputational model
Cite
SoFAR with DIM agents: An agent framework for distributed information management
Cite
Texture Content-Based Retrieval Using Content Descriptions
Cite
Semiotics and agents for integrating and navigating through multimedia representations of concepts
Cite
Modelling Learning for Intelligent Software Agents: A Connectionist Approach
Cite
MAVIS 2: a new approach to content and concept based navigation
Cite
Connectionist Models for Learning Choice Behaviour in Reactive Software
Cite
A flexible architecture for content and concept based multimedia information exploration
Cite
Flexible Features in Texture Similarity
Cite